The index finger and ring finger lengths were measured on the palmar surface of hands from the basal crease proximal to the palm to the tip of the finger using vernier calipers measuring to 0.01mm as described by Manning. Traditional risk factors for CAD such as diabetes mellitus, hypertension, hypercholesterolemia, hypertriglyceridemia and smoking were defined as we previously described. Study interpretation on severity of coronary artery stenosis was conducted by 2 expert readers. Subjects without CAD were those without stenosis in any branch. The area under the curve of right hand 2D:4D in male was 0.72 (95% CI 0.683-0.753, p50% stenosis in more than one epicardial branch as revealed by coronary angiography. On the right hand in the control group and on both hands in the CAD group, the 2D:4D ratios were higher in women than in men (all, P 0.05). A significant difference of 2D:4D ratios between right and left hand were observed only in men in both control and CAD groups. Results: There were no significant differences in age among the four groups. The receiver operator characteristic curves (ROCs) were used to detect the diagnostic effect of 2D:4D for CAD. Student t test was used to detect the difference of 2D:4D among groups. Finger lengths were measured twice for both hands using electronic calipers. Methods: This study included 1764 persons divided into 4 groups, 441 cases with CAD and 441 persons without CAD as control in each sex of the same age. We investigated whether 2D:4D could be used as a marker for predisposition to CAD as assessed by coronary angiography in Chinese men and women.
File import instruction Abstractīackground: The association between index finger to ring finger length ratio (2D:4D) and cardiac disorders has been reported, however it has not been discussed in terms of coronary artery disease (CAD). Select the file that you have just downloaded and select import option Reference Manager (RIS). The Ratio of Second to Fourth Digit Length (2D:4D) and Coronary Artery Disease in a Han Chinese Population. Wu Xl, Yang Dy, Chai Wh, Jin Ml, Zhou Xc, Peng L, Zhao Ys.
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